Zona Glomerulosa

The zona glomerulosa produces aldosterone.

Aldosterone production is mainly under influence of the renin–angiotensin–aldosterone system.

 

 

Aldosterone release is under angiotensin II and K+ regulation.

• Specificity of the mineralocorticoid receptor is conferred by specificity in tissue distribution and localized conversion of glucocorticoids to cortisone by 11β-hydroxysteroid dehydrogenase.
• Aldosterone increases renal sodium reabsorption and in exchange stimulates potassium excretion.
• Aldosterone originates from chlesterol
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